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CJC-1295 (no DAC), Ipamorelin 10mg (Blend)

CJC-1295 (no DAC), Ipamorelin 10mg (Blend)

€95.00

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Description

Buy CJC-1295 (No DAC) and Ipamorelin 10mg Blend Online | High Purity Research Peptides EU

 Dual GHRH/GHSR Signaling Blend | ≥99% HPLC/MS Certified | For Laboratory Research Only

Introduction: The Synergy of Dual-Receptor Activation in Endocrine Research

For researchers across Europe investigating the complexities of the growth hormone (GH) axis, the combination of CJC-1295 (No DAC) and Ipamorelin represents a sophisticated tool for dual-receptor pathway mapping. At eupeptideshop.org, we provide premium, high-purity peptide blends designed to support advanced in vitro and in vivo studies.

This blend combines a growth hormone-releasing hormone (GHRH) analog with a selective ghrelin receptor (GHSR) agonist. The synergistic action allows scientists to model the pulsatile nature of GH secretion more accurately than single-agent protocols . By simultaneously stimulating the pituitary via two distinct upstream pathways, researchers can analyze second-messenger kinetics, feedback loops, and the integration of GHRH–GHSR signaling in controlled experimental models.

For those looking to buy peptides EU with guaranteed compliance and purity, this blend is an essential addition to your laboratory’s repertoire.

Product Specifications & Technical Data

When sourcing research chemicals EU compliant, precise analytical data is non-negotiable. Below are the verified specifications for our CJC-1295 (No DAC) and Ipamorelin 10mg Blend.

Parameter Details
Product Name CJC-1295 (No DAC) / Ipamorelin 10mg Blend
Composition 5 mg CJC-1295 (No DAC) + 5 mg Ipamorelin (per vial)
Total Peptide Content 10 mg (lyophilized powder)
Purity ≥99% (Verified by HPLC and MS, per component)
Appearance White to off-white lyophilized powder
Storage (Lyophilized) Store at ≤ -18°C (0°F) in a dry, dark place. Stable for up to 24 months.
Storage (Reconstituted) Store at 2-8°C (36-46°F). Use within 30 days. Do not freeze after reconstitution.

Component A: CJC-1295 (No DAC) – Modified GRF (1-29)

  • Molecular Formula: C₁₅₂H₂₅₂N₄₄O₄₂

  • Molecular Weight: ~3367.95 g/mol

  • CAS Number: 863288-34-0

  • Sequence: Tyr-Ala-Asp-Ala-Ile-Phe-Thr-Asn-Ser-Tyr-Arg-Lys-Val-Leu-Gly-Gln-Leu-Leu-Ser-Ala-Arg-Lys-Leu-Leu-Gln-Asp-Ile-Leu-Ser-Arg

  • Function: A synthetic analog of GHRH without the Drug Affinity Complex (DAC). This “No DAC” variant offers a shorter half-life, making it ideal for studying acute GH pulse dynamics and avoiding prolonged receptor desensitization in culture .

Component B: Ipamorelin

  • Molecular Formula: C₃₈H₄₉N₉O₅

  • Molecular Weight: ~711.9 g/mol

  • CAS Number: 170851-70-4

  • Sequence: Aib-His-D-2-Nal-D-Phe-Lys-NH₂

  • Function: A pentapeptide known as a highly selective GHSR-1a agonist. Unlike earlier secretagogues (like GHRP-6), Ipamorelin demonstrates high selectivity for GH release with minimal effect on cortisol, prolactin, or ACTH in research models .

Research Applications & Investigational Pathways

As a leading peptide supplier Spain and across the continent, we understand that our clients require depth in research applications. This blend is frequently cited in scientific literature for the following investigational purposes:

  • Dual-GPCR Signaling: Study the interaction between GHRH receptors and ghrelin receptors (GHSR) on somatotroph cells .

  • Pulsatile GH Modeling: Investigate the summation of signals—how continuous GHRH stimulation (CJC-1295) combines with acute GHSR pulses (Ipamorelin) to shape GH release patterns .

  • Muscle and Bone Research: Preclinical models have utilized Ipamorelin to examine its effect on counteracting glucocorticoid-induced muscle loss and supporting bone formation, particularly when combined with a GHRH analog .

  • Metabolic Studies: Exploration of the metabolic-reproductive axis, insulin sensitivity, and body composition changes resulting from elevated IGF-1 downstream of GH pulses .

  • Cellular Repair and Recovery: Investigation into the role of GH/IGF-1 modulation on tissue regeneration and cellular repair mechanisms .

Handling, Reconstitution & Safety Protocols

Proper handling ensures the integrity of your research. This protocol is derived from best practices observed in laboratory peptides Netherlands and across top European research facilities.

Reconstitution Guidelines:

  1. Preparation: Remove the plastic flip-top cap from the vial. Swab the rubber stopper with an alcohol swab and allow it to dry.

  2. Diluent: Using a sterile insulin syringe, slowly inject 2-3 mL of bacteriostatic water (containing 0.9% benzyl alcohol) into the vial. Aim the stream against the inner glass wall to avoid shocking the peptide .

  3. Dissolution: Do not shake vigorously. Gently swirl or rotate the vial in your hands until the powder is completely dissolved and the solution is clear. Shaking can cause denaturation of the peptide structure .

  4. Final Concentration: If using 2 mL of diluent, the final concentration will be 5 mg/mL (2.5 mg/mL CJC-1295 + 2.5 mg/mL Ipamorelin). Using 3 mL yields a concentration of approximately 3.33 mg/mL.

Solubility Profile:

  • CJC-1295 (No DAC): Highly soluble in sterile water, bacteriostatic water, and sterile saline.

  • Ipamorelin: Highly soluble in sterile water. Acetate salts are common; if dissolution is difficult, a minimal amount of dilute acetic acid (0.1M) can be used as a pre-wet before final dilution with buffer, though sterile water is usually sufficient .

Safety & Compliance for European Researchers
This product is sold strictly as a research chemical EU compliant with REACH regulations.

  • Handling: Always use personal protective equipment (gloves, lab coat, safety glasses) when handling peptides.

  • Usage: For in vitro and laboratory animal use only. Not for human or veterinary use.

  • Waste Disposal: Dispose of all sharps and biological waste according to your local institutional and EU guidelines.

Why Choose eupeptideshop.org for High Purity Peptides?

As a premium peptide supplier based in the EU, we bridge the gap between global manufacturing standards and European research needs.

  • Verified Purity: We provide access to HPLC/MS verification data, ensuring you receive the high purity peptides Germany and France demand .

  • European Warehousing: Stock located within the EU ensures fast, reliable shipping without the delays or customs issues associated with international orders.

  • Compliant Labeling: All products are labeled and sold explicitly for Research Use Only (RUO), aligning with research chemicals EU compliant standards.

  • Expert Formulation: Our blends are PhD-reviewed to ensure accurate ratios for consistent experimental results .


Frequently Asked Questions: CJC-1295 & Ipamorelin Blend

Q1: Where can I buy CJC-1295 and Ipamorelin blend online in Europe?
A: You can buy this high-purity blend directly from eupeptideshop.org. We are a trusted EU-based supplier offering fast, discreet shipping across the Eurozone, including Germany, France, Spain, and the Netherlands.

Q2: What is the difference between CJC-1295 with DAC and No DAC?
A: The “No DAC” (No Drug Affinity Complex) variant is a shorter-acting GHRH analog. It provides a pulse of GHRH stimulation without binding to albumin for extended release. This is often preferred for research aiming to mimic the body’s natural pulsatile GH secretion patterns rather than a flat, continuous elevation .

Q3: What purity level do our products guarantee?
A: We guarantee a purity of ≥99% for each component, verified by High-Performance Liquid Chromatography (HPLC) and Mass Spectrometry (MS). This ensures that your research results are attributable to the peptides themselves, not to impurities .

Q4: How should I store the CJC-1295/Ipamorelin blend upon arrival?
A: Upon receiving your order, store the lyophilized (powder) vial in a freezer at ≤ -18°C. Keep it protected from light and moisture. Once reconstituted with bacteriostatic water, it should be stored in a refrigerator at 2-8°C and used within 30 days .

Q5: Is this product legal to purchase for research in the EU?
A: Yes. This product is sold as a chemical reagent for laboratory research purposes only. It complies with EU chemical regulations (REACH) and is not intended for food, medical, or veterinary use. By purchasing from eupeptideshop.org, you confirm that you are an authorized researcher.

Q6: How do I calculate the correct dose for my in-vitro study?
A: After reconstitution with 2 mL of bacteriostatic water, your solution concentration is 5 mg/mL. For example, if your protocol requires a 100 µg dose, you would draw 0.02 mL (2 IU on an insulin syringe) into your syringe. We recommend using a peptide dosage calculator for accuracy.

Q7: Do you ship peptides for research to France and Germany?
A: Absolutely. We specialize in shipping peptides for research France, high purity peptides Germany, and to all major EU countries. Our logistics are optimized for quick delivery while maintaining peptide stability.

Q8: What are the known research applications for Ipamorelin?
A: Ipamorelin is studied as a selective GHSR agonist. Research applications include investigating bone formation, gastric motility, and its role in stimulating GH without significantly affecting other appetite-related pathways compared to other GHRPs .

Q9: Can I use this product for human consumption or athletic performance?
A: No. This product is strictly for laboratory research use only. It is not a dietary supplement, pharmaceutical, or cosmetic. It is not intended for human consumption or athletic performance enhancement.

Q10: What is the peptide sequence for Ipamorelin?
A: The amino acid sequence for Ipamorelin is Aib-His-D-2-Nal-D-Phe-Lys-NH₂. This specific structure allows for its high selectivity at the ghrelin receptor  ........ .. ..  google

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........ .. ..  google

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