Description

Buy Density Labs LGD-4033 Ligandrol | High-Purity SARM for Research

Introduction
buy LGD-4033 Ligandrol EU, Welcome to eupeptideshop.org, your premier source for premium research compounds in the European Union. If you are looking to buy LGD-4033 Ligandrol online, you require a partner who understands the stringent demands of laboratory research. Density Labs LGD-4033 (Ligandrol) is a high-affinity, nonsteroidal selective androgen receptor modulator (SARM) primarily utilized for investigational purposes in muscle wasting and bone density studies .

As a trusted peptide supplier Spain and across the continent, we ensure that every batch of our research SARMs EU compliant meets the highest analytical standards. Our Ligandrol is synthesized for the explicit purpose of laboratory peptides Netherlands quality and high purity peptides Germany expectations. We supply to verified researchers requiring peptides for research France and throughout the EU. Trust eupeptideshop.org for pharmaceutical-grade reference materials designed to advance scientific discovery.

Technical Data Sheet

To ensure your research yields reproducible and reliable data, Density Labs LGD-4033 adheres to strict pharmacological specifications.

• Molecular Formula: C14H12F6N2O

• Molecular Weight: 338.25 g/mol

• CAS Number: 1165910-22-4

• Synonyms: LGD-4033, Ligandrol, VK5211

• Purity Specifications: Verified at >99% via High-Performance Liquid Chromatography (HPLC) and Mass Spectrometry (MS). This purity ensures the removal of synthetic impurities and solvents, critical for accurate in-vivo and in-vitro studies .

• Appearance: Solid crystalline powder .

• Solubility Profile:

  • DMSO: Soluble at ≥ 100 mg/mL (295.64 mM) .

  • Ethanol: Soluble at 60 mg/mL (177.38 mM) .

  • Water: Insoluble .

  • Note: For in-vivo formulations, co-solvents such as PEG400, Tween-80, or cyclodextrin are recommended to achieve clear solutions .

• Stability & Storage:

  • Powder Form: Stable for up to 3 years when stored at -20°C, desiccated and protected from light .

  • In-Solution: Stable for up to 6 months at -80°C, or 1-3 months at -20°C. Aliquot to avoid repeated freeze-thaw cycles which degrade the compound .

Known Research Applications

LGD-4033 has been the subject of numerous peer-reviewed studies due to its high specificity for the androgen receptor (Ki = 1 nM) . Current research vectors include:

• Muscle Wasting (Cachexia): Studies investigate its role in promoting muscle protein anabolism without the androgenic side effects on tissues like the prostate .

• Bone Density (Osteoporosis): Research indicates LGD-4033 exhibits both anti-resorptive and anabolic activity in bone tissue, making it a candidate for osteoporosis therapy .

• Metabolic Studies: Recent 2025 publications in the European Journal of Pharmacology have explored Ligandrol’s protective role against pancreatic β-cell toxicity and its potential to enhance glucose tolerance, highlighting novel applications in type 2 diabetes mellitus (T2DM) research due to androgen receptor activation .

• Endurance & Physiology: Contrary to popular belief, recent animal studies suggest that while Ligandrol increases grip strength, it may reduce submaximal endurance and maximal oxygen consumption (VO2max), providing critical data for sports science and physiology research .

Handling Protocols & Reconstitution Guidelines

As a leading research chemicals EU compliant supplier, we emphasize the importance of proper handling to maintain compound integrity.

1. Safety & Handling: LGD-4033 is a potent research compound. Use appropriate personal protective equipment (PPE) including nitrile gloves and safety goggles. Conduct all handling in a well-ventilated fume hood to avoid inhalation of particulates. This product is strictly for laboratory research use only and is not for human consumption.

2. Reconstitution:

   • Calculate the required concentration based on your molarity needs. For example, to make a 10 mM stock solution, dissolve 3.3825 mg of the compound in 1 mL of DMSO.

   • Allow the vial to warm to room temperature in a desiccator to prevent moisture condensation.

   • Add the calculated volume of anhydrous DMSO (or Ethanol for specific assays) directly to the vial.

   • Gently swirl or vortex until the powder is fully dissolved. For stubborn particulates, brief warming in a 37°C water bath and ultrasonication can aid solubility .

3. Dilution & Dosing: For in-vivo animal trials, further dilute the DMSO stock solution in a vehicle like saline, PEG300, or corn oil. The final concentration of DMSO should typically be kept below 10% to avoid vehicle-induced toxicity .

Why Purchase From eupeptideshop.org?

When you buy research peptides EU from us, you are choosing verified quality. We are not just another storefront; we are a dedicated peptide synthesis Europe partner. Our Density Labs line ensures that researchers in Belgium, Italy, Sweden, and across the continent receive products that meet the rigorous demands of modern science.

• Verified Purity: Each batch is accompanied by Certificates of Analysis (CoA) detailing HPLC/MS results.

• EU Warehousing: Fast, discrete, and reliable shipping from within the EU, ensuring no customs delays.

• Compliance: All products are marketed to laboratories and research institutions in compliance with EU chemical regulations.

Choose eupeptideshop.org for your next study. Buy LGD-4033 Ligandrol today and advance your research with confidence.

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Frequently Asked Questions (FAQ) Section

1. Is LGD-4033 the same as Ligandrol?
Yes, LGD-4033 is the chemical name, while Ligandrol is the generic or brand name commonly used in research literature. Both refer to the selective androgen receptor modulator with the CAS number 1165910-22-4 .

2. What purity level is required for reliable SARM research?
For reproducible and publication-ready data, a purity of at least 98% is essential to ensure that biological activity is not confounded by synthesis by-products. All Density Labs products available at eupeptideshop.org are verified at >99% purity via HPLC/MS, meeting the standards of top research peptides EU laboratories .

3. How should I store LGD-4033 powder upon delivery?
Upon receiving your order from our peptide supplier Spain warehouse or German distribution hub, store the powder desiccated at -20°C. Avoid exposure to light and humidity. Under these conditions, the compound is stable for several years. Once reconstituted in DMSO, it should be aliquoted and used within 1-3 months .

4. What is the solubility of Ligandrol for in-vivo animal studies?
While LGD-4033 is highly soluble in DMSO, DMSO can be toxic in live animal models if used at high concentrations. For in-vivo work, it is standard practice to prepare a concentrated stock in DMSO, then dilute it into a vehicle like PEG400, Tween-80, or aqueous cyclodextrin solutions to achieve a final clear solution with a safe DMSO percentage .

5. Can LGD-4033 be used in cell culture experiments?
Yes. For in-vitro work, dissolve the compound in DMSO to create a sterile stock solution. Due to its mechanism as an androgen receptor modulator, it is typically used at nanomolar concentrations. Always include vehicle controls to account for any effects of the solvent.

6. Do you ship to my country?
We specialize in supplying laboratory peptides Netherlands, peptides for research France, high purity peptides Germany, and all EU member states including Austria, Denmark, Finland, and Portugal. Shipping is fast and reliable from within the EU.

7. Is this product safe for human consumption?
No. Density Labs LGD-4033 is a high-purity chemical synthesized strictly for in-vitro and in-vivo laboratory research purposes only. It is not a pharmaceutical preparation for humans or animals. It is explicitly not for human consumption, veterinary use, or any clinical application . The World Anti-Doping Agency (WADA) prohibits its use in sports .

8. Where can I find reliable research on LGD-4033?
Peer-reviewed research is available through databases like PubMed. Recent studies have investigated its role in glucose regulation (type 2 diabetes mellitus) and its physiological effects on endurance, providing a broad spectrum of scientific data outside of just muscle physiology .

9. What is the half-life of Ligandrol in research models?
Human clinical studies have indicated that LGD-4033 possesses a long terminal half-life, approximately 24 to 36 hours, allowing for once-daily dosing in research models investigating lean body mass. However, half-life can vary significantly between species ........ .. ..  google